Startups Directory

Thanks to plant-based biotechnologies and a licensing-based model, Serendip Innovations helps therapeutic asset developers design better products, safer and easier to manufacture.

Thanks to plant-based biotechnologies and a licensing-based model, Serendip Innovations helps therapeutic asset developers design better products, safer and easier to manufacture.

Better pharmaceutical products, better impact on patients

2,700,000 €

3,000,000 €

Limbium is a health-tech startup transforming upper-limb prosthetics through advanced engineering, digital manufacturing and full personalization. We design and produce three types of prosthetic solutions (bionic, sports and biomechanical) all lightweight, functional and tailored to each user. Our products are 100% publicly subsidized in Spain, making high-quality prosthetics accessible to everyone. As the only manufacturer of upper-limb sports prostheses in Europe, we combine patented technology with a fast, affordable and user-centric workflow. Our mission is to empower people with limb differences to regain independence, performance and quality of life.

Limbium is a health-tech startup transforming upper-limb prosthetics through advanced engineering, digital manufacturing and full personalization. We design and produce three types of prosthetic solutions (bionic, sports and biomechanical) all lightweight, functional and tailored to each user. Our products are 100% publicly subsidized in Spain, making high-quality prosthetics accessible to everyone. As the only manufacturer of upper-limb sports prostheses in Europe, we combine patented technology with a fast, affordable and user-centric workflow. Our mission is to empower people with limb differences to regain independence, performance and quality of life.

Our technology generates a strong social impact by making high-quality upper-limb prosthetics accessible to everyone, regardless of income or location. By reducing costs, personalizing each device and shortening delivery times, we help people with limb differences regain independence, mobility and confidence. This leads to better health outcomes, improved employability and greater participation in social and sport activities. Additionally, our sports prostheses promote inclusion in athletics, enabling amputees to compete, train and perform at a higher level. Ultimately, Limbium reduces inequalities and enhances quality of life at scale

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MiWEndo is a medical technology startup transforming colorectal cancer prevention with a microwave imaging and AI system that detects lesions invisible to standard colonoscopy. Our device provides functional, 360° information beyond optical imaging, enabling higher detection rates. We operate under a razor-and-blade model with strong clinical traction and a clear path to CE marking.

MiWEndo is a medical technology startup transforming colorectal cancer prevention with a microwave imaging and AI system that detects lesions invisible to standard colonoscopy. Our device provides functional, 360° information beyond optical imaging, enabling higher detection rates. We operate under a razor-and-blade model with strong clinical traction and a clear path to CE marking.

MiWEndo enables a safer and more reliable colonoscopy by detecting flat, hidden and low-contrast polyps that currently go unnoticed. This directly reduces preventable colorectal cancers and enables earlier, more accurate decision-making. Patients benefit from fewer complications, fewer unnecessary resections and earlier treatment when needed. Hospitals benefit from improved diagnostic efficiency and reduced downstream costs. At a population level, it contributes to more effective screening programs and a significant public-health impact through better prevention.

€1.5M

€5M

Mential is a precision mental health company developing a clinical-grade Digital Twin platform powered by AI. Our technology transforms text, voice, audio and behavior and sensor data into 1,300+ structured FHIR markers, enabling continuous monitoring, early risk detection and fully digital treatment pathways. We provide hospitals, insurers, pharma and research centres with scalable clinical intelligence, automated supervision tools and high-resolution behavioral data. Mential has a strategic focus on women’s mental health, addressing major unmet needs across anxiety, depression, maternal health and menopause.

Mential is a precision mental health company developing a clinical-grade Digital Twin platform powered by AI. Our technology transforms text, voice, audio and behavior and sensor data into 1,300+ structured FHIR markers, enabling continuous monitoring, early risk detection and fully digital treatment pathways. We provide hospitals, insurers, pharma and research centres with scalable clinical intelligence, automated supervision tools and high-resolution behavioral data. Mential has a strategic focus on women’s mental health, addressing major unmet needs across anxiety, depression, maternal health and menopause.

Mential’s technology will have a significant societal impact by making mental healthcare more accessible, personalised and scalable. By enabling continuous monitoring, early risk detection and adaptive digital treatment, Mential reduces the burden of untreated mental health problems, lowers relapse rates and helps people recover faster. For health systems, it increases clinical capacity (2–3× more patients per clinician) and reduces costs, helping hospitals and insurers serve more people with fewer resources. For vulnerable populations, especially women, it provides tailored support for conditions like anxiety, depression, maternal mental health and menopause—addressing long-standing gender gaps in mental-health research and care. For employers and public institutions, it reduces absenteeism, improves wellbeing and supports healthier, more resilient communities. For science and industry, Mential generates high-resolution behavioural data and validated digital biomarkers, accelerating research, innovation and evidence-based policy-making. Mential contributes to a healthier, more equitable and more productive society by enabling earlier intervention, better outcomes and broader access to high-quality mental health support.

€250.000

€500.000

Spin-off biotecnológica de ICO-IDIBELL centrada en el desarrollo de una nueva terapia contra un mecanismo de resistencia en cáncer colorrectal avanzado, combinada con un biomarcador de selección de pacientes, con modelo de negocio basado en licencias a grandes farmacéuticas y servicios de I+D/consultoría en oncología.

Spin-off biotecnológica de ICO-IDIBELL centrada en el desarrollo de una nueva terapia contra un mecanismo de resistencia en cáncer colorrectal avanzado, combinada con un biomarcador de selección de pacientes, con modelo de negocio basado en licencias a grandes farmacéuticas y servicios de I+D/consultoría en oncología.

National health system

€1M

€4M

Processing/Management/Valorization of farming manure, slurry, and whey from cheese making

Processing/Management/Valorization of farming manure, slurry, and whey from cheese making

Reducing contamination and minimizing explotation of mineral resources to fertilize crops

€500.000

€500.000

NeuroshedBio is a Madrid-based platform company that generates next-generation human brain organoids from SHED (stem cells derived from exfoliated baby teeth) to accelerate neuroscience R&D. Our proprietary technology preserves each child’s genetic and epigenetic identity, enabling physiologically relevant models of neurodevelopmental disorders.

NeuroshedBio is a Madrid-based platform company that generates next-generation human brain organoids from SHED (stem cells derived from exfoliated baby teeth) to accelerate neuroscience R&D. Our proprietary technology preserves each child’s genetic and epigenetic identity, enabling physiologically relevant models of neurodevelopmental disorders.

NeuroshedBio accelerates the arrival of effective neurological treatments, advances precision medicine, and reduces the economic and ethical costs associated with current preclinical models of neurodevelopmental disorders .

€150K

NeuroshedBio is raising a €0.75M–€1.2M pre-seed round to validate our organoid platform, achieve our first pharma pilot, and build 18–24 months of runway toward a Seed round

Synthetic Data generation to optimize Clinical Trials

Synthetic Data generation to optimize Clinical Trials

Synthetrial's activity focuses on generating a positive and measurable impact on the healthcare system and society. The lack of representativeness in clinical, healthcare and cosmetic trials is a barrier to the development of effective and fair treatments. Synthetrial has a major social impact, targeting patients suffering from different diseases who take risks by participating in clinical trials that are likely to fail, or who do not even have access to innovative treatments because they belong to minority populations (rare diseases, pregnant women, paediatric patients, elderly people, etc.). The solution proposed by Synthetrial allows for the simulation of data from underrepresented patients, thereby contributing to more equitable access to biomedical innovation. Furthermore, by reducing the need for real data, it enables research in contexts where data is scarce. For example, data from pregnant women, a group systematically excluded for ethical reasons, can be simulated, facilitating the development of safe treatments without putting real people at risk. Pilots are also being conducted focusing on neurodegenerative diseases in older people, where recruitment difficulties limit clinical evidence. The technology also makes it possible to create synthetic histories of rare diseases, increasing the visibility and understanding of little-known pathologies, which can improve diagnosis, monitoring and treatment.

150.000 €

300.000 €

Developing therapies for unmet needs in oncology

Developing therapies for unmet needs in oncology

Improving clinical outcome of patiens

500.000 EUR

1 million EUR

eB 2 develops solutions for the management and improvement of mental health, emotional well-being, and occupational health through Artificial Intelligence and mobile technologies. We harness the power of Artificial Intelligence for mental health and emotional well-being. We transform data into actionable knowledge for healthcare professionals, clinical researchers, and academics.

eB 2 develops solutions for the management and improvement of mental health, emotional well-being, and occupational health through Artificial Intelligence and mobile technologies. We harness the power of Artificial Intelligence for mental health and emotional well-being. We transform data into actionable knowledge for healthcare professionals, clinical researchers, and academics.

eB2 MindCare directly addresses one of Europe’s most urgent social and health challenges: mental disorders affecting one in six citizens and costing over €600 billion annually. By enabling continuous, AI-driven mental-health monitoring, the platform supports early detection, prevention, and intervention, reducing crisis episodes, hospital readmissions, and suicide risk.

1,000,000€

BioEclosion’s patented magneto-actuated device integrates disposable magnetic-cartridge immunoassays with electrochemical readout to deliver lab-quality, quantitative results from a single drop of whole blood in about 10 minutes on a smartphone, enabling end-users to take immediate action at the point of need.

BioEclosion’s patented magneto-actuated device integrates disposable magnetic-cartridge immunoassays with electrochemical readout to deliver lab-quality, quantitative results from a single drop of whole blood in about 10 minutes on a smartphone, enabling end-users to take immediate action at the point of need.

Our technology will have a positive impact on society by making high-quality diagnostics more accessible, affordable, and integrated across sectors. Human health, veterinary diagnostics, food safety, and environmental control typically rely on separate, non-interoperable platforms, increasing cost and complexity. BioEclosion’s magneto-actuated device addresses this by offering a single, portable, quantitative, and easy-to-use platform that delivers rapid, reliable results from a small sample directly on a smartphone. This will enable earlier and more accurate clinical decisions, better monitoring of animal health, faster detection of contaminants in food and water, and improved environmental surveillance. Ultimately, it supports a One Health approach, strengthens outbreak preparedness, reduces inequalities in access to diagnostics (especially in low-resource settings), and improves overall public health and safety.

1M€

2.2M€

From Empirical to Digital At OPTICmizing, we digitalize and automate food industry processes traditionally managed by experience. Using advanced optical sensors and intelligent models, we turn data into precise, automatic decisions. We optimize every production stage—from raw material selection to packaging—enhancing quality, standardizing processes, and reducing costs, waste, and energy use. With our Industry 4.0 solutions, clients achieve more efficient, sustainable, and profitable operations. At OPTICmizing, vision and technology modernize the food industry.

From Empirical to Digital At OPTICmizing, we digitalize and automate food industry processes traditionally managed by experience. Using advanced optical sensors and intelligent models, we turn data into precise, automatic decisions. We optimize every production stage—from raw material selection to packaging—enhancing quality, standardizing processes, and reducing costs, waste, and energy use. With our Industry 4.0 solutions, clients achieve more efficient, sustainable, and profitable operations. At OPTICmizing, vision and technology modernize the food industry.

Less costs for industry, better prices for consumers. Also safer products in some cases...

300.000€

300.000€

Loomee Health is the copilot for mental health professionals, empowering them with explainable clinical intelligence. Our comprehensive platform combines management, evidence-based resources, and AI-powered monitoring to optimize intervention and decision-making.

Loomee Health is the copilot for mental health professionals, empowering them with explainable clinical intelligence. Our comprehensive platform combines management, evidence-based resources, and AI-powered monitoring to optimize intervention and decision-making.

Loomee has a positive impact, not only by providing the professional with 1 hour a day and improving the patient's quality of life (+15% adherence, -20% symptom reduction, -25% treatment duration), but also (potentially) reducing more than €900M in indirect costs for the public sector

€500.000

€500.000

Automate the operations carried out by pest control companies to monitor and surveil insects that transmit diseases.

Automate the operations carried out by pest control companies to monitor and surveil insects that transmit diseases.

We directly impact the use and handling of pesticides for pest control.

€135K

€150k

Horux Medical is a virtual university focused on healthcare areas that serves as a VR meeting point between students and experts physically located in different parts of the world. The instructor can design their rooms interactively by uploading their own anatomical models, marking regions of interest on them, and using basic scripting to record actions within the VR. The rooms configurable by the expert can be both theoretical and practical.

Horux Medical is a virtual university focused on healthcare areas that serves as a VR meeting point between students and experts physically located in different parts of the world. The instructor can design their rooms interactively by uploading their own anatomical models, marking regions of interest on them, and using basic scripting to record actions within the VR. The rooms configurable by the expert can be both theoretical and practical.

We enable any student or expert to share knowledge about a specific health area regardless of physical distance.

100,000 €

100,000 €