Startups Directory

Energy RIS is a certified "Emerging Company" providing Research and Intelligence Solutions to accelerate the global energy transition. We use our own software and hardware to transform complex data and deep expertise into actionable foresight, pioneering next-generation solutions in areas such as AI-driven smart grids, Energy-Water nexus, Citizen Energy Communities, and sustainable fuel development.

We tackle the multifaceted challenges of the global energy transition by: Flexible generation/consumption: Integrating high volumes of variable photovoltaics into complex and often isolated electric systems using AI, our own devices and predictive analytics. Empowering Local Energy: Providing the intelligence and models necessary to establish and scale profitable Citizen and Renewable Energy Communities, making clean power accessible and affordable for local consumers and businesses. Decarbonizing Hard-to-Abate Sectors: Developing the intelligence and solutions for the production and managing of water using renewable technologies and storage.

Our technology and solutions are designed to create a more resilient, sustainable, and equitable energy future by: Lowering Energy Costs: Enabling local energy generation and intelligent grid management to reduce electricity bills for citizens and businesses. Lowering water costs: Optimizing the energy-water nexus to achieve critical decarbonization goals. Empowering Citizens: Providing the tools and frameworks for communities to own, manage, and benefit directly from their local energy resources.

As we have largely bootstrapped our growth through R&D contracts and dedicated profits, this engagement is less about a traditional funding round and more about a strategic capital partnership for large-scale deployment. Indeed, we are seeking the strategic capital required to successfully execute a market acceleration plan: (1) Scale Global Reach: Rapidly deploy our AI-driven grid intelligence platforms across new international insular and decentralized markets; and (2) commercialize IP: Launch the commercial platform for managing Citizen and Renewable Energy Communities across Europe.

The total size of our current capital acceleration effort is specifically calibrated to meet our three major deployment milestones. Rather than targeting a round size, we define our capital requirement by the funding necessary to scale our proprietary AI models and hardware for high-penetration renewable energy integration across multiple international utility contracts, and fully commercialize our Citizen Energy Community management software platform for immediate market roll-out. This focused capital target reflects a highly efficient use of funds, designed to rapidly move our proven intelligence solutions from lab to market scale.

Nanological develops advanced solutions to transform the diagnosis of bacterial infections, with a strong focus on sepsis. Founded as a spin-off of the Spanish National Research Council (CSIC), the company commercializes a proprietary optomechanical sensing platform, exclusively licensed to Nanological and refined over more than a decade of research. This technology enables the rapid label-free characterization of individual cells and microorganisms directly from liquid samples by precisely measuring their mass, size, and optical absorption. Building on this core technology, Nanological is developing a novel point-of-care (POC) diagnostic device that integrates optomechanical sensing, disposable microfluidic cartridges, and AI-powered analysis software. The system is designed to identify pathogens directly from whole blood in under 30 minutes, dramatically reducing the 24–72 hours typically required by conventional blood culture methods. By advancing its technology toward industrial-scale manufacturing and working closely with hospitals and clinical partners, Nanological aims to accelerate the global adoption of rapid pathogen detection, ultimately improving diagnostic workflows and saving lives.

Sepsis is a life-threatening condition caused by a dysregulated immune response to infection, affecting around 50 million people worldwide and causing over 11 million deaths annually. Rapid and targeted treatment is critical, as every hour of delay in appropriate therapy increases mortality by 8%. However, current diagnostics based on blood cultures typically require 24-72 hours, forcing empirical use of broad-spectrum antibiotics, which can lead to suboptimal care and contribute to antimicrobial resistance. Hence, there is an urgent need for rapid point-of-care diagnostic tools that enable early pathogen identification for faster initiation of targeted treatment, improving patient outcomes and reducing healthcare costs through shorter hospital stays.

Our technology has the potential to significantly improve public health by enabling earlier and more accurate detection of life-threatening bacterial infections, such as sepsis. By reducing diagnostic time from days to minutes, it allows clinicians to initiate the appropriate treatment sooner, dramatically reducing mortality, preventing complications and shortening hospital stays. Faster, targeted diagnosis also reduces unnecessary antibiotic use, helping to combat antimicrobial resistance, one of the greatest global health challenges. Beyond individual patient outcomes, widespread adoption of rapid diagnostics can ease the burden on healthcare systems, lower costs, improve resource allocation in emergency and critical-care settings, and increase equity of access to high-quality care, particularly in regions with limited laboratory infrastructure. As the technology scales, its impact will extend to broader range of infectious diseases, strengthening global preparedness, surveillance and response capacity.

1.5M€

2M€

At Valyra Aerospace, we are developing the next generation of European-made Unmanned Aerial Systems, built around high endurance VTOL platforms capable of operating reliably in extreme and challenging environments. Our systems are designed for real-world surveillance, emergency response, security, and inspection missions, combining robustness, autonomy, and adaptability to deliver practical aerial solutions where they are needed most.

In Europe, naval operations such as border control, surveillance, and maritime logistics lack modern, cost-effective, and sea-resistant aerial platforms. Helicopters are expensive (>€15M), costly to operate (>€3,000/h), and have limited endurance (~4h). Conventional drones offer short flight times (<1h) and cannot withstand harsh maritime conditions. Additionally, Europe depends on foreign manufacturers, creating strategic vulnerability in terms of autonomy and sovereignty. Our technology addresses these gaps by providing robust, long-endurance VTOL UAS designed for real maritime and extreme-environment operations.

Our technology improves societal safety, security, and resilience by providing reliable aerial platforms for critical missions. With robust, long-endurance drones capable of operating in extreme environments, we strengthen European autonomy and technological sovereignty, enabling faster, more effective decision-making when lives and assets are at stake.

€500k

€1M

SmartYield is a geospatial intelligence platform that combines satellite data, climate information, and AI to monitor crops, forecast yields, and assess climate-related risks in real time. We help governments, companies, and farmers make faster and more informed decisions for food security.

SmartYield provides early crop forecasts, real-time climate-risk detection, and reliable field monitoring to reduce uncertainty in food production and water management.

SmartYield improves food security and climate resilience by enabling earlier, smarter agricultural decisions.

We are raising €800,000 to industrialize SmartYield, expand our satellite–climate AI pipelines, and scale deployments with institutional partners

€800,000

Naplatec develops and produces high-value ingredients for the cosmetic, nutraceutical and food industries. Crocins are the potent carotenoids behind saffron’s health and cosmetic benefits. Our patented platform delivers the benefits of these plant-based bioactives to a wider population through a cost-effective, sustainable, scalable process.

Crocins are highly-valued carotenoides, not only as pigments, but also for their health-promoting properties including antioxidant activity, neuroprotective, anti-inflamatory, cardioprotective, anti-depressant, anti-diabetic, anti-cancer and skin health. Crocins are used in food, cosmetic and nutraceutical industries. The current sources of crocins are saffron and gardenia, which are extremely low yielding, labour intensive, and expensive. Naplatec's unique platform provides a new cost-effective, scalable source of crocins which will make the benefits of crocins available to a wider population.

Saffron is the most expensive spice in the world, and this limits the potential of the application of saffron-based crocins and the ability of society to benifit from their health promoting properties. Our solution makes these bioactives more accessible, democratizing access to their therapeutic potential for diverse populations. The Naplatec project brings high-value agricultural activity in rural areas by integrating science and cultivation of a high value product. It promotes the economic activity of local tecnological industries in the extraction and formulation, and provides a new and sustainable source of crocins in Europe. Our platmore significantly reduce the environmental. Compared to traditional sources of crocins, our approach requires less water, land, and energy, while also lowering CO₂ emissions.

400.000€

400.000€

IGOID-SPORTEC is a spin-off company dedicated to quality control and research in sports surfaces.

Our services help to determine the condition of sports surfaces (e.g. deformity, shock absorption, etc.) and whether they comply with international standards.

New services help society to have access to optimal sports facilities that do not harm the health of their users.

N/A

N/A

SDB is dedicated to manufacturing play surfaces that guarantee safety and sustainability, protecting the integrity of users.

Our company was founded with the aim of responding to the problems caused in the sports surface sector by the ban on microplastics. Currently, a transitional period has been established for the phasing out of certain microplastics, including ‘granular infill for artificial turf pitches’, which will be banned as of 17 October 2031. This ban and the awareness of the relatively high toxicity of the components that make up standard artificial sports turf (virgin or recycled plastics) gave rise to the idea, previously developed through various European projects, of manufacturing these various components using bio-based compounds, resulting in a new product, innovative in the sector, which will be both recycled and recyclable.

Our company was founded with the aim of responding to the problems caused in the sports surface sector by the ban on microplastics. Currently, a transitional period has been established for the phasing out of certain microplastics, including ‘granular infill for artificial turf pitches’, which will be banned as of 17 October 2031. This ban and the awareness of the relatively high toxicity of the components that make up standard artificial sports turf (virgin or recycled plastics) gave rise to the idea, previously developed through various European projects, of manufacturing these various components using bio-based compounds, resulting in a new product, innovative in the sector, which will be both recycled and recyclable.

N/A

N/A

We transform waste into advanced carbon nanomaterials for next-gen batteries with fast charge and extended life.

The limitations of current battery technology: limited lifespan, slow charge and need for expensive minerals.

Removing polluting waste from the environment and turning it into high-value products. Enabling wider adoption of renewable energies and electric mobility by removing the limitations in energy storage technology.

Not currently looking for investment.

Not currently looking for investment.

High-performance fibre-optic sensors for extreme conditions

High-performance sensors for extreme temperature conditions

Sensors are required to monitor the sectors of energy, aerospace, construction etc. We can provide solutions for a better eficiency and developing a better society

2 million euros

4 million euros

We convert CO2 into Graphene Quantum Dots and Carbon Black at room temperature and without catalysts.

We produce Graphene Quantum Dots from CO2, of high quality and single fluorescent color, non toxic for biomedicine, scalable, and a lower cost than competition. We also produce sustainable Carbon Black particles for pneumatic tires, saving 7 tons of CO2 per ton of Carbon Black vs competition.

Our pure, single color, and low cost Graphene Quantum Dots may enable cancer imaging. This may be achieved with Red GQDs linked to AI design small proteins that recognize cancer. Our sustainable Carbon Black can have a positive impact on climate change. Fox example, EU produces ~2.4 Gt. CO2 per year, and EU climate plans aims to reduce 55% these emissions by 2030, which means reducing ~132M tons/year. Our Carbon Black technology would reduce 54-81M tons/year CO2.

€3M

€3M

Deeptech startup focused on early dementia screening

Lack of objective and early diagnostic tools

Reducing diagnosis times and the costs associated with patient care, and improving the quality of life of patients and their families

€100.000

€100.000

ANT is a technology-based spin-off of GTT , headquartered in Extremadura and with strong traditional ties to the region. It is a founding member of the Extremadura agricultural cluster and the National Association of Precision Agriculture (ANAP), and a member of the European Semiconductor Association (AENEAS. ANT, in collaboration with the University of Extremadura (UEx) and the Extremadura Center for Scientific and Technological Research (CICYTEX), has developed a laboratory prototype of ELECTRONIC-NOSES applied to the cultivation and indsutrial transformation of tomatoes. This development has been funded by the European Penta cluster of Eureka within the PLANtAR project and is nearing completion (October 2023), with results at a TRL 4 maturity stage and Junta de Extremadura by the project IDA3-23-003-3.

Optimization of sensory quality of tomato´s products

Optimization in tomato production and in the organoleptic quality of its products

500.000 euros

500.000 euros

Nexyra Advanced Research is a multi-omics AI company that integrates molecular and clinical data through systems biology to generate actionable insights for biomedicine. We identify robust biomarkers, prioritize therapeutic targets, and build predictive/prognostic models to accelerate translational research, clinical development, and precision medicine especially in complex, heterogeneous diseases.

We accelerate biomarker discovery, target prioritization, and predictive model development by integrating multi-omics and clinical data into actionable systems-level insights.

Nexyra’s technology has the potential to create societal impact by making precision medicine more effective, faster to deliver, and more accessible—especially in complex diseases. Better patient outcomes: By integrating multi-omics and clinical data, we enable more accurate biomarkers and predictive models, supporting earlier diagnosis, improved risk stratification, and better treatment selection. Faster, more efficient drug development: Our systems-level target prioritization and translational analytics can reduce false leads, shorten R&D cycles, and increase the probability of success in clinical development—helping new therapies reach patients sooner. Lower healthcare costs through smarter decisions: More precise patient stratification and response prediction can reduce ineffective treatments, avoid unnecessary procedures, and improve resource allocation. Equity and scalability in biomedical insight: Automating complex multi-omics interpretation helps democratize advanced analysis beyond top-tier institutions, enabling broader participation in research and clinical innovation. Acceleration of biomedical knowledge: By turning high-dimensional biological data into actionable, mechanistic insights, we help research teams move from data to decisions faster, strengthening translational pipelines and scientific productivity.

320.000€

720K €

We build AI modules to make autonomous interceptor drones.

Protecting critical infrastructure from small drone threats.

It will keep our energy, travel, communications and trade infrastructure secure. Allowing us to keep our way of life.

€1M

€3M

Our startup aims to help SMEs leverage the opportunities that Artificial Intelligence (AI) technologies have matured in the last few years, such as Large Language Models, cloud-based services and AI-enhanced optimization search, making them affordable and accessible to SMEs. Moreover, the close collaboration with academic research will enable the startup to develop various AI plugins dedicated to ecommerce platforms to increase sales and improve performance, with components that understand users' purchasing habits to improve commercial offerings and provide Business Intelligence, Management Control and Content Marketing toolkits for Ecommerce Managers.

The opportunity lies in the massive and underserved Small Medium Enterprises (SMEs) ecommerce market that is currently excluded from AI-driven optimization due to cost and complexity barriers. In Italy only 18% of SME have an ecommerce and only 7% of them use AI to sell online (Techbusiness.it). The digital transformation acceleration, particularly post-pandemic, has created urgent demand among SMEs to optimize their online presence and sales processes, yet most lack the technical expertise or financial resources to implement enterprise-level AI systems. In this scenario, SMEs are struggling to compete against AI-powered large corporations, there exists a significant market gap for accessible, affordable AI solutions specifically designed for their capabilities and budgets. With our project we want to offer actively plug-and-play solutions that can help SMEs deliver immediate Return Of Interest (ROI) without requiring extensive technical knowledge or massive upfront investments.

Our AI venture benefits society by making powerful business intelligence and optimization tools available to small and medium-sized businesses—tools that were once only accessible to large corporations. This helps level the playing field, supports economic diversity, and gives more businesses a fair chance to compete. By helping businesses use their resources more efficiently, reduce waste, and improve operations, the platform supports environmental sustainability and creates ripple effects that boost local economies and enhance sustainability. It also helps generate higher-skilled jobs and gives consumers better, more personalized shopping experiences. Importantly, the platform provides transparent, easy-to-understand information to eCommerce managers, giving them greater autonomy and supporting informed decision-making reducing their reliance on dominant platforms like Amazon or eBay where sellers often have less control

500.000€

700.000€