Patent
US6402947

INTERPHASE DEVICE FOR THE DIRECT COUPLING OF LIQUID CHROMATOGRAPHY AND GAS CHROMATOGRAPHY

TRL 4 – technology validated in lab

The basic structure of a PTV (programmed temperature vaporizer) injector has been considerably modified so that is can be used for the direct coupling of liquid chromatography in normal phase or reverse phase, and gas chromatography and also for the introduction of high volumes in gas chromatography. The glass tube of the injector is filled with an adsorbent. By means of a system of valves and tubes or capillary tubes, the previously selected fraction of liquid chromatography is transferred to the injector, said fraction coming in through the same extremity for introducing the gas chromatography column. The eluent is entrained by a gas stream through the adsorbent, wherein are retained the solutes, and the solvent is removed through a tube or capillary tube introduced in the injector through the opposite extremity. Thereafter, the solutes are desorbed thermally passing to the chromatography column.

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TRL 4 – technology validated in lab
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The purpose of the research group is to develop new analytical strategies with low environmental impact based on the implementation of sustainable sample preparation methods and their analysis by (micro)-separative techniques that are characterized by low solvent consumption and reagents. These analytical strategies are aimed at chiral analysis, the search for biomarkers, the obtaining of bioactive substances or the revaluation of waste in order to apply them to the resolution of current problems in different fields of high social interest: food, pharmaceutical, cosmetic, agrochemical. , environmental.
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