Microencapsulation of active compounds in natural-origin substrates

Patent number:

ES2764623

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Microencapsulation of active compounds into matrices is a technology used in applications such as different sectors like pharmaceutical, agri-food, or phytosanitary. Microspheres degradation releases the active principle along the time in the needed concentration. A broad range of applications can be observed, in the above-mentioned sectors being, biocide, antioxidants, healing or functionalized nanoclay. Despite of the undeniable usage, recent studies suggest that, although microspheres represent just a small percentage of plastic rejected to the oceans, lakes, and rivers, because of their amount, they might be a risk. Microspheres go down to drain, and numerous wastewater treatment plants cannot filtrate them, meaning that small plastic wastes reach easily the riverbed. Besides, certain chemicals are adhered to these microbeads in oceans and river beds, which might lead to be ingested by fishes, and potential introduction to the food chain. The proposed colophony microspheres provide advantages over these problems due to the natural origin (coming from non-fossil fuels), its biocompatibility being adequate for pharmaceutical and health applications, and, additionally, because of the biodegradability which provides zero waste in the middle and long term. Finally, colophony shows significant advantages when it is applied with electrospraying generating optimal spheres distribution onto the substrate. This procedure ensures the ulterior homogeneous and regular active compound release.

Countries:
Spain
Regions:
Valencian Community
Centers:
UNIVERSITAT DE VALENCIA, FISABIO, UNIVERSITAT POLITECNICA DE VALENCIA
Other entities:
Sectors:
Chemicals
Subsectors:
Basic materials chemistry, Surface technology, coating
TRL Level:
TRL 4 – technology validated in lab
BRL Level:
PDF Link:
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Video Link:
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Sustainable Development Goal:
SDG12: Responsible consumption and production
Applications

ADVANTAGES The electrospraying technique using colophony as matrix shows the following advantages: - Electrospraying does not produce chemical by-products on the final material in contrast to chemical techniques used to produce microspheres. - Bead size is significant smaller from those obtained for mechanical atomizer system, and with low standard deviation. - Colophony comes from natural origin (no synthetic). - And it is more economical than other natural materials. BUSINESS APPLICATIONS · Companies from the following sectors: pharmaceutical, cosmetic, agri-food or phytosanitary.

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