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Diagnostic procedure for the determination of the Nox2 protein
Patent number:
EP3495821A1
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A diagnostic method for the quantitative detection of the Nox2 protein in a biological sample, comprising the following operations i) normalize the protein content of the biological sample to a value of 1 μg of protein per 100 μl of sample, ii) put in contacting the normalized biological sample with an anti-Nox2 monoclonal detection antibody, wherein the detection antibody is directly conjugated to a detection label, and iii) detecting the formation of the Nox2 protein-detection antibody complex.
Countries:
Italy
Regions:
No items found.
Centers:
SAPIENZA UNIVERSITA DI ROMA
Other entities:
Sectors:
Health
Subsectors:
Biotechnology, Analysis of biological materials
TRL Level:
TRL 6 – technology demonstrated in relevant environment (industrially relevant environment in the case of key enabling technologies)
BRL Level:
BRL1: Hypothesizing on possible business concept
PDF Link:
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Applications
The patent is applicable in the field of cardiovascular and inflammatory disease. In particular, the sNox2-dp analysis by ELISA Kit can help to stratify the cardiovascular and inflammatory risk.
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