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USE OF BACTERIA OF THE GENUS TENACIBACULUM FOR QUORUM QUENCHING
Patent number:
US2011195051B, CN102149395B, EP2356991B
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Use of bacterial cells of the genus Tenacibaculum, from the crude cellular extract or from its cultivation supernatants, capable of degrading N-acyl homoserine lactones, for quorum quenching, for treatment of infectious bacterial illnesses or to inhibit formation of biofilms.
Countries:
Spain
Regions:
Galicia
Centers:
UNIVERSIDAD DE SANTIAGO DE COMPOSTELA
Other entities:
Sectors:
Food & Agro
Health
Subsectors:
Biotechnology
TRL Level:
TRL 4 – technology validated in lab, TRL 5 – technology validated in relevant environment (industrially relevant environment in the case of key enabling technologies)
BRL Level:
PDF Link:
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Applications
Use of this technology to block the processes controlled by AHL-mediated quorum sensing, providing a promising treatment for inhibiting biofilm formation as well as for controlling animal pathogens This represents a cheaper and more sustainable alternative than the use of antibiotics in animals, reducing the costs and occurrence of antibiotic residues and lowering the probability of antibiotic-resistant bacteria.
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