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HYDROGELS FOR THE PRODUCTION OF ARTIFICIAL TISSUE WITH ENHANCED MECHANICAL PROPERTIES
EP22382231.3
A method for the preparation of hydrogels suitable for producing artificial tissues has been developed. The method combines fibrin, fibrinogen and shortchained peptides, which interact to enhance cell adhesion and proliferation. The resulting tissues could be used as a medicine for organ regeneration, and could restore the functional activity of a damaged or diseased organ.
- Enhanced biomechanical properties The use of short-chain peptides improves the mechanical strength of the material, and does not depend on agarose concentration, that would worsen the porosity. - Adequate porosity Allowing cell growth in the material - Biocompatibility Thanks to the interactions between fibrin, fibrinogen and peptides, biocompatibility improves in comparison to current solutions.