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12-DEOXYPHORBOL DERIVATIVES AND USES THEREOF
Patent number:
WO22144482
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The invention relates to the synthesis and use of 12-DEOXYPHORBOL derivatives (or phorbol esters) to promote the differentiation of neurons from neural precursors or neural stem cells in culture and in the adult brain. The invention also relates to the use of the same type of compound for the preparation of a pharmaceutical composition useful in the treatment of damage to the central nervous system involving neuronal loss.
Countries:
Spain
Regions:
Andalusia
Centers:
UNIVERSIDAD DE CADIZ, UNIVERSIDAD DE SEVILLA
Other entities:
Sectors:
Health
Subsectors:
TRL Level:
TRL 4 – technology validated in lab
BRL Level:
PDF Link:
Download hereVideo Link:
Watch it hereSustainable Development Goal:
SDG03: Good health and well-being
Applications
Improvement of the impairment caused by the loss of neurons associated with aging and neurodegenerative diseases.
Comments
P202031312