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In vitro method to predict and/or forecast the compatibility of biomaterials in a subject
P202130407 - PCT/ES2022/070279
The present invention relates to a set of proteins that is particularly useful for predicting and/or predicting the in vitro compatibility of a biomaterial used as an implantable medical device, such as any type of prosthesis, such as stents, cannulas, pacemakers, dental implants. etc. Additionally, the present invention also comprises an in vitro method to predict and/or predict the compatibility of said biomaterials by determining and quantifying the peptide profile adhered to said Biomaterials, as well as a kit and/or device to carry out said method. .
A personalized regeneration capacity test developed for patients who are going to receive an implant or prosthesis can avoid undesired mishaps and enable significant time and cost savings. Sectors for commercial application: Prosthetics production industrial sector - On the one hand, the method would be of interest to companies that manufacture dental implants, hip prostheses, knee prostheses and, in general, all producers of materials that are going to be in contact with bone. - On the other hand, it may also be useful for companies that manufacture percutaneous medical devices, such as dental implant abutments and catheters. Research sector. - Any groups performing in vitro and in vivo tests applied in the development of new biomaterials in order to determine their capacity for tissue regeneration. Healthcare sector. - In particular, dental clinics, hospitals and stakeholders.