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MULTI-LAYERED CELL CAPSULES AND USES THEREOF
Patent number:
EP19382785
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The present invention provides a hydrogel capsule comprising a cell, a protein, and a cross-linking agent; wherein the cell is within a first core layer comprising the protein; and wherein the first core layer is surrounded by a second layer comprising the protein and the cross-linking agent. The invention further provides the hydrogel capsule for use in therapy, prognosis and diagnosis, a method for culturing cells, a method for differentiating cells, and method for producing the hydrogel capsule. The hydrogel capsules of the invention are particularly useful for encapsulating pancreatic islets.
Countries:
Spain
Regions:
Catalonia
Centers:
FUNDACIO INST DE BIOENGINYERIA DE CATALUNYA IBEC
Other entities:
Sectors:
Health
Subsectors:
Biotechnology
TRL Level:
TRL 5 – technology validated in relevant environment (industrially relevant environment in the case of key enabling technologies)
BRL Level:
PDF Link:
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Applications
multi-layered hydrogel cell capsules that increase cell viability and biocompatibility, in particular pancreatic islets.
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