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ORGANOID CULTURE SYSTEM AND METHOD FOR STERILISING AN ORGANOID CULTURE SYSTEM
ES2746033A1
The invention relates to a modular sterilisable system for organoid culture, which comprises a culture module with one or more sample wells and an agitation module that includes an air compressor with flow control means, a nozzle for each sample well, a pressure sensor and a controller that acts on the flow control means according to the pressure reading. The method for sterilising the system consists in decoupling the two modules, removing the culture module and sterilising it. The system can have a module for monitoring the growth of the organoids, as well as a module for controlling the physiochemical parameters of the culture.
The present invention describes a system for organoid culture that allows simultaneous high-throughput, reuse of standard culture material and equipment, as well as real-time monitoring of organoid growth and physical parameters -Relevant chemicals. Furthermore, the system is modular and one module can be sterilized independently of another.