Precursor compounds for providing retinoids of the vitamin a5 pathway and uses thereof

Patent number:

WO2018091937

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The invention relates to the field of retinoid X receptor (RXR) signalling and a novel vitamin A pathway called Vitamin A5 pathway. Compounds which are useful to provide (R) 9-cis-13,14-dihydro-retinoic acid an endogenous RXR ligand are claimed as well as their uses and method for preparation thereof. The compounds of the invention are useful for pharmaceutical and nutritional uses.

Countries:

Spain

Regions:

Galicia

Centers:

UNIVERSIDAD DE VIGO, DE STRASBOURG UNIV

Other entities:

University of Debrecen; Universite de Strasbourg; Debreceni Egyetem

Sectors:

Health

Subsectors:

Biotechnology

TRL Level:

TRL 4 – technology validated in lab

BRL Level:

PDF Link:

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Video Link:

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Sustainable Development Goal:

Applications

The invention relates to the field of retinoid X receptor (RXR) signalling and a novel vitamin A pathway called Vitamin A5 pathway. Compounds which are useful to provide (R) 9-cis-13, 14-dihydro-retinoic acid an endogenous RXR ligand are claimed as well as their uses and method for preparation thereof. The compounds of the invention are useful for pharmaceutical and nutritional uses.

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