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NeoMag
NeoMag® is a breakthrough instrumentation platform that provides non-invasive, remote, and programmable mechanical stimulation of biological systems in 2D and 3D cultures. Developed from ERC-funded research (4D-BIOMAP and ISBIOMECH), the system utilizes proprietary magneto-active polymers (MAPs) as intelligent, ultra-soft cell scaffolds. The core scientific achievement is the ability to recreate complex, dynamic, and physiologically relevant mechanical microenvironments—such as the stiffness changes and strain patterns seen in tumor progression, traumatic brain injury, or cardiac fibrosis—directly within standard incubators.
NeoMag® is a plug-and-play instrumentation platform designed for high-throughput, non-invasive mechanical stimulation of cell cultures. Its practical applications include:
- Drug Discovery & Oncology: Testing drug efficacy in "stiff" tumor-like environments to study invasion and chemoresistance, improving the predictive power of preclinical assays.
- Neuroscience: Simulating the physical forces of Traumatic Brain Injury (TBI) and strokes non-invasively to study neuroinflammation and develop protective therapies.
- Tissue Engineering: "Programming" the maturation of artificial skin, muscle, or bone constructs by applying physiological loads to smart scaffolds.
- In Vitro Modeling: Replacing static culture plates with dynamic environments that mimic the human body, directly reducing the cost of clinical failures and the reliance on animal testing.
