Startups Directory

We help companies to stop firefighting and start building with purpose by teaching them thinking in systems through practical training.

Companies’ departamental misalignment, operational&processes deficiencies, internal communication.

Thanks to the clarity that companies gain, the alignment between employees and companies improves, creating a common purpose and improving the workplace for people. Not to mention a new ability to think in systems, therefore obtaining independency to solve any problem on their own (both for companies and their employees).

Bootstrapping

N/A

SMART Fusion Energy is committed to making fusion a practical reality—delivering clean, safe, and virtually limitless energy through the world’s most compact and efficient fusion power plants. Born as a spin‑off from the University of Seville, SMART Fusion Energy leverages the groundbreaking advances of the SMART (SMall Aspect Ratio Tokamak) ecosystem, transforming the high‑field, negative‑triangularity spherical tokamak—a configuration proven to boost plasma stability and power handling—into commercial fusion technology. With the SMART tokamak’s unique plasma‑shaping capability and world‑leading experimental results, the company accelerates the journey from frontier research to deployable fusion energy systems. SMART Fusion Energy is currently engineering the first European fusion pilot plant, positioning itself at the forefront of the global race toward sustainable, on‑demand fusion power.

Clean, sustainable, and affordable energy production.

SMART Fusion Energy aims at realising fusion as a clean and virtually unlimited energy source via the most compact and efficient possible fusion power plant.

5 M€

20%

Bioceanics is a groundbreaking spin-off from Universidad Autónoma de Madrid offering a sustainable and more effective alternative to traditional omega-3 sources. Our innovative enzymatic and non-enzymatic processes convert fish or algae oil into a bioequivalent of krill oil omega-3, eliminating the need to capture krill while providing the same high-quality benefits.

Much of the world's population exhibits low blood levels of the omega-3s EPA & DHA. Omega-3 fatty acids are essential nutrients for maintaining human health, and are primarily obtained through the consumption of fatty fish or supplements. The bioavailability and efficacy of omega-3 supplements can vary depending on the source, lipid form and processing methods used.

Bioceanics solutions have a range of positive effects and impacts, encompassing environmental, health, and economic aspects. These effects include: Environmental Impact; Conservation of marine ecosystem, Reduction of overfishing and Minimization of ecological Health Impact: Improved access to high-quality Omega-3 and Enhanced health benefits. Economic Impact: Market growth and opportunities along with Cost efficiency

1.5M€

1.5M€

It's a biotechnology company where we've developed a bioinformatics software called Al-Awal. This software incorporates an artificial intelligence engine that allows us to optimize all types of proteins with 98% effectiveness, based on the ribosomal pause theory. It's a physical-deterministic model that breaks with existing practices, bringing innovation and efficiency to the pharmaceutical industry.

It solves the problems of protein synthesis in the pharmaceutical industry, since with this optimization we achieve synthesis on the first attempt in 98% of cases, saving time and money.

It will help produce safer and more efficient drugs and vaccines, reducing the environmental impact and carbon footprint by reducing the number of attempts in protein synthesis.

500.000€

500.000 €

AI sales platform for trade shows

Automate sales contact un top of funnel

Help companies to growth faster

150.000€

150000€

We provide software for battery manufacturers based on AI algorithms that predict energy consumption and generation and optimize the use of the batteries

Grid stabilization, consumption optimization, energy efficiency

It will help improve the use of energy in a more efficient way, eventually preventing blackouts and lowering electric bills

None for now

0€

ReCero is a social impact startup that promotes a new way of managing pharmaceutical waste through technology, incentives, and data. We install smart collection points in pharmacies that identify returned medicines, generate metrics on adherence, consumption, and recycling, and reward responsible patients.

ReCero addresses a critical blind spot in the pharmaceutical system: the lack of visibility and data on what happens to medicines after they are dispensed. In addition, it tackles the challenge of proper pharmaceutical waste recycling by enabling source-separated disposal at the pharmacy level, ensuring safer, more efficient, and environmentally responsible management of medicine residues.

ReCero generates positive societal impact by improving how medicines are managed once they leave the healthcare system. By promoting proper, source-separated recycling of pharmaceutical waste, ReCero reduces environmental contamination and supports more sustainable use of healthcare resources. At the same time, the data generated through the recycling process enables better understanding of medicine consumption patterns, adherence, and waste, helping healthcare systems make more informed, evidence-based decisions.

ReCero is seeking €150,000–€250,000 in this round. This funding will be used to finance a real-world pilot with pharmacies, further develop the technological platform, ensure regulatory and operational readiness, and generate the first validated impact and data needed to scale.

The total size of the round is €250,000, designed to fully fund a real-world pilot, validate impact, and prepare the solution for scale.

Agrivoltaics that scale

Agrovoltaics is too cost intensive for it to scale. It relies on trackers or in exotic solar panels.

By making Agrivoltaics more easy to adopt for farmers we empower distributed generation and energy communities.

250000€

500000€

Virtual GaP substrates on Si for electronics and photonics

Reduction in the price of substrates for the integration of photonics and electronics, and more specifically, of III-V and silicon technologies

This technology will reduce the final price of products that require photonic and electronic devices

1€

1€

Ownmed Innovation is a Madrid-based MedTech spin-off company arising from a strategic alliance between the Foundation for Biomedical Research of Hospital Gregorio Marañón (FIBHGM), the Fundación Jiménez Díaz Health Research Institute (IIS-FJD), and Universidad Carlos III de Madrid (UC3M). Ownmed operates in the medical devices sector, with a strong focus on patient-centered clinical innovation, and its mission is to develop advanced technological solutions that significantly improve the quality of life of people living with chronic conditions.

currently rely on passive collection systems, which have significant limitations such as leaks, skin irritation, recurrent infections, and a high psychological and social impact. Ownmed was founded based on the direct clinical experience of its CEO, Ana Ye—a nurse and biomedical engineer—who recognized these unmet needs in her patient care practice. In response, the company developed Ostofix, an anti-reflux medical device that allows patients to control continence and choose when to evacuate, preventing involuntary waste release and providing greater autonomy, safety, and well-being.

Ostofix is set to transform ostomy care by providing patients with active control over continence, improving quality of life, autonomy, and psychosocial well-being, while reducing complications such as leaks, skin irritation, and infections. Pre-clinically validated and in clinical validation, it integrates biomedical materials, and innovative device design, generating high-value evidence and advancing the state of the art in medical devices. Economically, Ostofix strengthens Spain’s medtech sector by creating highly skilled jobs, attracting private investment, and reducing dependence on foreign technologies. It also supports healthcare system sustainability by lowering complication-related costs and enabling more efficient resource use. Overall, Ostofix positions Ownmed as a leader in biomedical innovation and serves as a model for public-private collaboration in advanced healthcare solutions.

1.500.000€

1.500.000€

We measure and optimize carbon emissions from digital services improving at the same time Business KPIs and reducing operational costs.

We measure and optimize carbon emissions from digital services improving at the same time Business KPIs and reducing operational costs.

Hiili solutions reduce the energy consumption and carbon emissions associated to digital services that will have a positive impact in mitigating global warming and climate change

1 million €

TBD

Our startup focuses on the development of digital health solutions to improve mental healthcare through technology and data. We combine expertise in artificial intelligence, behavioural science, and mobile technologies to create innovative tools for early detection, continuous monitoring, and personalized intervention in mental health. Our mission is to empower clinicians and patients by providing accessible, science-based solutions that enhance decision-making and treatment outcomes.

eB2 MindCare addresses several key challenges in the field of mental health: Delayed detection of mental health issues, due to limited access to professionals and underreporting of symptoms. Lack of continuous and objective monitoring outside of clinical settings. Low adherence to treatment plans and difficulty in personalizing interventions. Fragmentation of data, which hinders clinical decision-making and follow-up. By leveraging smartphone sensors and AI, eB2 MindCare provides real-time behavioural insights and facilitates early intervention, improving care efficiency, personalization, and long-term outcomes for patients.

eB2 MindCare has the potential to generate a significant positive impact on society by promoting early detection and prevention in mental health, reducing the burden on healthcare systems, and improving patients' quality of life. By enabling continuous and remote monitoring, it empowers individuals to better understand and manage their mental well-being, while supporting professionals with data-driven insights. The platform integrates digital biomarkers and AI models to provide real-time KPIs, including: Suicide risk levels based on behavioural patterns, emotional state indicators, functionality metrics.

500.000 € - 1.000.000 €

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A high-precision, portable pulse oximeter, with 4 LEDS, powered by artificial intelligence and machine learning, for continuous measurement of oxygen saturation and heart rate.

Our purpose is to overcome the limitations of traditional oximeters, which fail in critical situations such as low oxygen levels, high heart rates, intense movement, and dark skin.

The greatest impact of our technology on society is that it avoids the technological discrimination caused by the inaccuracy of pulse oximeters based on skin color, facilitates the rehabilitation of people with respiratory problems, and helps with home monitoring of sick people.

At Altum Sequencing we revolutionize cancer monitoring after diagnosis and treatment. Using cutting-edge DNA sequencing, we can detect a single tumor cell among a million healthy ones—from just a simple blood sample.

Conventional follow-up often misses tiny signs of cancer or gives unclear results, forcing invasive tests and slowing decisions. Altum turns a simple blood sample into clear, patient-specific signals that reveal relapse earlier and guide the next step. This reduces uncertainty, avoids unnecessary procedures, and lowers overall care costs.

By finding cancer’s return earlier from a simple blood sample, our technology helps patients start the right treatment sooner, with fewer invasive procedures and less anxiety. Clinicians get clearer decisions, hospitals reduce avoidable tests and costs, and health systems gain scalable, data-driven follow-up. Over time, this improves outcomes, broadens access to precision care, and makes cancer monitoring more humane, efficient, and sustainable.

5.000.000€

We currently have an open investment round of €5 million. The previous round was €600,000.

Sustainable solutions for wastewater regeneration. Company in the environmental engineering sector dedicated to the design, construction and marketing of electroactive biofilters for water regeneration.

METfilter® systems degrade waste through natural metabolic processes, reducing or eliminating the pollutant load of domestic (grey and black) or industrial (hydrocarbons, pharmaceuticals, solvents) water. This versatility allows us to offer solutions to a wide variety of clients, from industries in the petrochemical sector to the food industry (wineries, breweries, dairy) or the pharmaceutical industry, not forgetting the urban sector (municipalities, campsites, housing developments, small rural communities and even private homes). METfilter® systems are decentralized solutions, custom-designed to adapt to waters of different natures, with low operating costs and no production of waste such as sludge.

Metland technology has a positive impact on society by reducing environmental pollution, improving wastewater management, and protecting public health. It supports sustainable development, and contributes to a better quality of life while promoting environmentally responsible practices.

500000 - 1000000 EUR

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