USE OF A NEUROPEPTIDE IN THE PREVENTION AND / OR TREATMENT OF DISORDERS AND EFFECTS RELATED TO ALCOHOL.

Patent number:

P201731170

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El alcohol es una de las drogas con mayor consumo a nivel global, siendo la responsable de una gran cantidad de problemas relacionados con la salud. A pesar del gran impacto socio-económico que conlleva el consumo de alcohol, se carece de tratamientos efectivos para su adicción. Recientemente se empiezan a considerar a los neuropéptidos como piezas clave en algunas enfermedades neuropsiquiátricas, entre las que se encuentra el alcoholismo, y por tanto, dianas clave donde encontrar nuevos tratamientos. En estudios recientes en modelos animales, se propone el uso del fragmento de Galanina (1-15) como terapia capaz de producir una disminución del consumo voluntario de alcohol así como una gran disminución de la preferencia por esta sustancia. Concretamente, la presente invención propone el uso de Galanina (1-15) para disminuir de una forma rápida la preferencia y el consumo de alcohol en personas con uso abusivo de alcohol.

Countries:
Spain
Regions:
Andalusia
Centers:
UNIVERSIDAD DE MALAGA
Other entities:
Sectors:
Health
Subsectors:
TRL Level:
TRL 4 – technology validated in lab
BRL Level:
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Sustainable Development Goal:
Applications

- Currently, there are only three drugs approved for the treatment of alcoholism, but none of them is certainly effective. The appearance of a new drug capable of reducing the preference and consumption of alcohol quickly, as demonstrated in pre-clinical studies, would be a great advantage for the treatment of alcoholism and its associated pathologies. - Given that the effect of Galanin (1-15) in alcoholism seems to be related to a depletion of the natural reinforcement system, its use would not only help to reduce the consumption of alcohol but also of other substances of abuse that are consumed together with is.

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