Use of acylated aminoacids as nutraceutical approach to prevent mild cognitive impairment

AAME has a natural origin, is concentrated in selected foods and its administration does not cause changes in the behavior, weight, or appearance of treated subjects. OLE’s value proposal is superior to other nutraceuticals-nootropics due to: - oral administration and easy intestine absortion - It crosses the blood-brain barrier (BBB) - It instructs the immune system (microglia) to encapsulate and eliminate toxic protein aggregates - Promotes neuroprotection against oxidative stress - Improves the cognitive abilities of administrated subjects In summary, unlike the active ingredients present in other commercial nutritional supplements, OLE has the ability to modify the course of cognitive decline and Alzheimer's disease.