Faecal microbiota signature for pancreatic cancer

Patent number:

WO2023/052486

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The CNIO has developed a method for early detection of pancreatic cancer. The inventors have found a method for early diagnosing pancreatic cancer based on a faecal microbiota signature with high specificity for pancreatic cancer.

Countries:
Spain
Regions:
Community of Madrid
Centers:
CNIO, FUNDACION CNIO
Other entities:
EUROPEAN MOLECULAR BIOLOGY LABORATORY
Sectors:
Health
Subsectors:
Biotechnology
TRL Level:
TRL 3 – experimental proof of concept
BRL Level:
PDF Link:
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Video Link:
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Sustainable Development Goal:
Applications

The method of the invention is a sensitive, specific and non-invasive method for an early detection of pancreatic cancer, in particular Pancreatic Ductal Adenocarcinoma (PDAC) that could therefore improve survival outcomes. The present invention refers to a method for diagnosing pancreatic cancer in a subject comprising determining the abundance of several Microbiome species in a faecal sample from said subject, as well as to a kit and its use for the diagnosis of pancreatic cancer.

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