SIGNATURE FOR THE PROGNOSIS OF BRAIN METASTASIS RELAPSE

Patent number:

WO/2025/008525

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The CNIO has developed a signature that allows the significant determination of the risk of relapse of brain metastasis after treatment. The inventors have found a method for the prognosis of brain metastasis relapse and to a kit useful in said prognosis based on a gene signature.

Countries:

Spain

Regions:

Community of Madrid

Centers:

CNIO, FUNDACION CNIO

Other entities:

Sectors:

Health

Subsectors:

Biotechnology

TRL Level:

TRL 3 – experimental proof of concept

BRL Level:

PDF Link:

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Video Link:

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Sustainable Development Goal:

Applications

The inventors have found that analyzing the expression levels of the genes of the signature of the present invention in an isolated sample from a subject who underwent treatment, for example brain surgery, constitutes a reliable method for the prognosis of brain metastasis relapse in the subject. The signature of the present invention is therefore the basis of a reliable method and kit for the prognosis of brain metastasis relapse after treatment, and more particularly, after brain surgery.

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