CELL THERAPY FOR THE TREATMENT OF SPHINCTER DYSFUNCTIONS

Fecal incontinence (FI) is a type of sphincter deficiency disorder that consists in disabling condition for affected patients that translates into a significant deterioration in quality of life, social isolation and depressive symptoms. The current treatment for patients with damaged sphincters is surgical repair. The observed problem is that the success rate is relatively moderate after the procedure. It has been associated with high morbidity, perioperative complications and a high failure rate. Through preclinical and clinical trials, cell therapy treatment is being evaluated, although the results obtained are promising, the procedure has room for improvement, since there is no certainty that the injected cells will remain at the injection site long enough to regenerate the affected tissue, and the ratio still needs to be improved. cost-effectiveness of treatment. This invention has developed a treatment based on cell therapy, in which the characteristics and composition of the cell suspension have improved the therapeutic effect, increasing the regeneration of injured muscle tissue.