IN VITRO METHOD FOR QUANTIFYING THE CELLULAR CONTENT OF SPECIFIC RNAS

Patent number:

PCT/EP2022/068795

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The present invention refers to an in vitro method for quantifying total cell RNA content, preferably total cell content of long-non-coding RNAs (lncRNA), more preferably total cell content of lncRNA molecules transcribed from telomeric or sub-telomeric sequences or present in telomeric regions, such as TERRA and/or TERC.

Countries:

Spain

Regions:

Community of Madrid

Centers:

UNIVERSIDAD AUTONOMA DE MADRID

Other entities:

Sectors:

Health

Subsectors:

TRL Level:

TRL 4 – technology validated in lab

BRL Level:

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Sustainable Development Goal:

SDG03: Good health and well-being

Applications

The invention refers to an in vitro method for quantifying the cellular content of a given RNA in a size independent manner. Specifically, the cellular content of long-non-coding RNA (lncRNAs), preferably total cellular content of lncRNA molecules transcribed from telomeric or sub-telomeric sequences, or present in telomeric regions, such as TERRA and/or TERC, can be quantified according to the present invention. It can be applied in biomedical field.

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