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IN VITRO METHOD FOR QUANTIFYING THE CELLULAR CONTENT OF SPECIFIC RNAS
PCT/EP2022/068795
The present invention refers to an in vitro method for quantifying total cell RNA content, preferably total cell content of long-non-coding RNAs (lncRNA), more preferably total cell content of lncRNA molecules transcribed from telomeric or sub-telomeric sequences or present in telomeric regions, such as TERRA and/or TERC.
The invention refers to an in vitro method for quantifying the cellular content of a given RNA in a size independent manner. Specifically, the cellular content of long-non-coding RNA (lncRNAs), preferably total cellular content of lncRNA molecules transcribed from telomeric or sub-telomeric sequences, or present in telomeric regions, such as TERRA and/or TERC, can be quantified according to the present invention. It can be applied in biomedical field.