COMBINED THERAPY COMPRISING AN INHIBITOR OF INTERLEUKIN-17 ACTIVITY AND A VITAMIN D RECEPTOR AGONIST

Patent number:

EP4037690

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The invention relates to a combined therapy including an inhibitor of interleukin-17 (IL-17) activity for use in combination with a vitamin D receptor agonist in the prevention and/or treatment of diseases or conditions known as autoimmune and autoinflammatory concomitant diseases, such as autoimmune kidney diseases, autoimmune joint diseases, skin autoimmune diseases, autoimmune neurological diseases, autoimmune thyroid diseases, and gout disease. The invention provides also the combination for use in the treatment and/or prevention of cancer, in which deregulation of immune system takes place. The invention also relates to the therapeutic combination and to its use in the treatment or prevention of proteinuria.

Countries:
Spain
Regions:
Balearic Islands
Centers:
FUNDACIO INST DINVESTIGACIO SANITARIA ILLES BALEARS
Other entities:
Servei de Salut de les Illes Balears; Fundación para la Investigación Biomédica del Hospital Universitario Ramón y Cajal
Sectors:
Health
Subsectors:
TRL Level:
TRL 4 – technology validated in lab
BRL Level:
PDF Link:
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Video Link:
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Sustainable Development Goal:
Applications

The invention relates to a combined therapy including an inhibitor of interleukin-17 (IL-17) activity for use in combination with a vitamin D receptor agonist in the prevention and/or treatment of diseases or conditions known as autoimmune and autoinflammatory concomitant diseases, such as autoimmune kidney diseases, autoimmune joint diseases, skin autoimmune diseases, autoimmune neurological diseases, autoimmune thyroid diseases, and gout disease. The invention provides also the combination for use in the treatment and/or prevention of cancer, in which deregulation of immune system takes place. The invention also relates to the therapeutic combination and to its use in the treatment or prevention of proteinuria.

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