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METHOD AND SYSTEM FOR MEASURING THE DYNAMICS OF MESOPIC CONTRAST SENSITIVITY RECOVERY
WO21209669
A method and system for the implementation thereof is disclosed, which rapidly provides simultaneous information on the functioning of both the external and internal retina. It comprises the brief dazzling of the eye of a subject with a light source, to cause a temporary insensitivity to contrast, and to psychophysically, automatedly measure the contrast during a period of time and the moment in time when said subject detects successive visual stimuli, modulated in contrast and presented against a background of mesopic luminance. The responses provided by the subject during the recovery of the contrast sensitivity, measured by the cones of the retina, are recorded in order to obtain distinguishing parameters of this dynamics of recovery, and to compare them with a standardised database to detect disturbances in visual function typical of neurodegenerative diseases of the retina.
While others methods use dark conditions and punctual light stimuli to measure during 30 minutes the recovery of light sensitivity mediated by the rods of the retina, this invention uses conditions of mesopic light, a measurement time of 5 minutes and stimuli with a detection characteristic that vary in contrast to identify delays in the rate of recovery of contrast sensitivity mediated by retinal cones. Simultaneously, it allows to identify a worsening of the final mesopic contrast threshold and therefore alterations of the contrast mechanism processed by the ganglion cells of the internal retina. The invention has been designed for its application in the diagnosis of alterations in visual function, the origin of which is It may be due to the external retina, internal retina or both, in the field of ophthalmology or optometric clinic. Among pathologies of interest include age-related macular degeneration, diabetic retinopathy and glaucoma among others.
The invention has been tested with more complex equipment in a laboratory environment. need development for adapt the computerized system to a simpler clinical environment and development of the computerized implementation for
perform the method