Faecal microbiota signature for pancreatic cancer

Patent number:

WO2023/052486 (A1)

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The inventors have found a method for early diagnosing pancreatic cancer based on a faecal microbiota signature with high specificity for pancreatic cancer.

Countries:

Spain

Regions:

Community of Madrid

Centers:

SPANISH NATIONAL CANCER RESEARCH CENTRE, CENTRO NACIONAL DE INVESTIGACEIONES ONCOLOGICAS CNIO

Other entities:

EUROPEAN MOLECULAR BIOLOGY LABORATORY

Sectors:

Health

Subsectors:

Biotechnology

TRL Level:

TRL 4 – technology validated in lab

BRL Level:

PDF Link:

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Video Link:

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Sustainable Development Goal:

Applications

The method of the invention is a sensitive, specific and non-invasive method for an early detection of pancreatic cancer, in particular Pancreatic Ductal Adenocarcinoma (PDAC) that could therefore improve survival outcomes. The present invention refers to a method for diagnosing pancreatic cancer in a subject comprising determining the abundance of several Microbiome species in a faecal sample from said subject, as well as to a kit and its use for the diagnosis of pancreatic cancer.

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