AN AZAPYRIDINOPHAN COMPOUND AS AN ANTIFUNGAL

Patent number:
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Fungal infections are a common health problem that can affect people of all ages and genders. Fungal infections, also known as mycoses, are caused by different types of fungi that can invade the skin, nails, hair and other parts of the body. These infections can range from mild and bothersome to serious and potentially dangerous if they are not treated properly. Treatment requires antifungals topically, orally or intravenously in more severe cases. Fungal infections are difficult to treat due to the similarity between fungal and human cells, so the search for compounds that would be effective against fungi and also safe for humans is complicated. Currently, only four families of compounds are available for the treatment of systemic infections caused by fungi,azoles, echinocandids, pyrimidines and polyenes. However, these drugs show adverse effects ranging from mild to severe. Furthermore, the emergence of resistance to antifungals has important implications for the morbidity and mortality of mycoses. Therefore, there is a need to find new, safer and more specific treatments.

Countries:
Spain
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Centers:
UNIVERSITAT DE VALENCIA, UNIVERSITAT ROVIRA I VIRGILI
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Sectors:
Health
Subsectors:
TRL Level:
TRL 2 – technology concept formulated
BRL Level:
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Applications

The main advantages provided by the invention are: · Lower toxicity than reference compounds. · Lower treatment costs and easier to produce. · Easily scalable production of the compounds. The main application of the technology is in the pharmaceutical and/or veterinary sector, as a drug or active ingredient for the treatment of fungal infections in humans and/or animals.

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