METHOD FOR THE PRODUCTION OF COMPLEX REPERTOIRES OF RECOMBINANT MOLECULES

Patent number:

ES2456823B1; WO14044892

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The invention relates to a method for the production of complex repertoires of recombinant molecules in a consistent and reproducible manner, comprising the transient generation of multi-transgenic plants that generate somatic mosaics induced by viral replicons that are mutually exclusive. The invention also relates to the multi-transgenic plant or a fragment of same obtained in this way, as well as to extracts or purified fractions thereof, which represent complex repertoires of recombinant molecules, preferably recombinant proteins selected from among: enzymes, immunoglobulins, membrane receptors, intracellular receptors, lectins, polyclonal antibodies, antidotes based on anti-serums, immunological serums for passive immunity, and intravenous immunoglobulins.

Countries:
Spain
Regions:
Canary Islands
Centers:
UNIVERSIDAD DE LAS PALMAS DE GRAN CANARIA, CSIC, UNIVERSITAT POLITECNICA DE VALENCIA
Other entities:
Sectors:
Health
Subsectors:
TRL Level:
TRL 3 – experimental proof of concept
BRL Level:
PDF Link:
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Video Link:
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Sustainable Development Goal:
SDG03: Good health and well-being
Applications

La ventaja de la presente invención, es que hoy en día es muy demandadas las moléculas recombinantes, para su uso en diversos sectores como el farmacéutico, veterinario, energético, etc. Esta metodología ayuda a producir repertorios complejos de diferentes proteínas, de modo que la composición final de la mezcla sea altamente reproducible, para su utilización.

Comments

La presente invención se realizó conjuntamente con el CONSEJO SUPERIOR INVESTIGACIÓN CIENTÍFICA; UNIVERSIDAD POLITÉCNICA DE VALENCIA Y UNIVERSIDAD DE LAS PALMAS DE GRAN CANARIA

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