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NANOSTRUCTURE LIPID SYSTEM
EP19736745; US17259110
The present invention is related to systems of administration of enzymes or other proteins, preferably for use in enzyme replacement therapy (ERT), in particular for the treatment of Lysosomal diseases. In particular, the invention encompasses the preparation of a composition based on nanostructured lipid systems and its use in the manufacture of a therapeutic product.
The invention is based on a specialized administration system for the lysosomal release of enzymes used in the enzymatic replacement treatment of lysosomal storage diseases. End users are patients who suffer EDLs diseases of which ERT therapy exists, as well as the national health systems that finance these treatments. The treatment of these diseases is throughout all of life since at the moment there is no curative therapy.