PEPTIDE AND PHARMACEUTICAL COMPOSITIONS OF SAME FOR USE AS AN ANTIMICROBIAL AND IN CANCER TREATMENT

The present invention concerns the development of a peptide for use as an antimicrobial in the treatment of Gram -, Gram + bacterias and fungus as well as effective for use in cancer treatment. Antimicrobial peptides (AMP) are good candidates as new antibiotic agents since they offer a mechanism of action different from conventional antibiotics and therefore they are excellent agents for preventing the development of antibiotic resistance. The rapid rate at which antimicrobial peptides promote cell death is an additional factor that contributes to reduce the chance of developing resistance. On the other hand, these peptides can also act synergistically with conventional antibiotics, enhancing their therapeutic activity. Moreover, the developed peptide has antiproliferative activity independent of the mostly mutated pathways in cancer, so its use together with existing chemotherapeutic agents would increase the effectiveness of cancer treatment and in particular breast cancer. Although other similar peptides had been studied before, until this invention no modified peptides had been developed with higher efficacy.