A SYNTHETIC HYDROGEL AND ITS USE FOR IMMUNOTHERAPY AND 3D-PRINTING

Patent number:

EP20382432

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The present invention discloses a hydrogel comprising a functionalized PEG multi- arm star polymer covalently combined with maleimide-functionalized low molecular weight heparin, further comprising at least one positively charged immune molecule, a method for producing this hydrogel and its use in T cell culture for immunotherapies. Furthermore, the invention relates to a bioink and its use in 3D-(bio)-printing.

Countries:
Spain
Regions:
Catalonia
Centers:
FUNDACIO INST DE BIOENGINYERIA DE CATALUNYA IBEC, CSIC, CT DE INVESTIGACIO BIOMEDICA EN RED DE ENFERMEDADES RARAS CIBERNED CENTRO DE INVESTIG BIOMEDICA EN RED ENFERMEDADES NEURODEGENERATIVAS, UNIVERSITAT POLITECNICA DE CATALUNYA
Other entities:
Sectors:
Health
Subsectors:
Biotechnology
TRL Level:
TRL 3 – experimental proof of concept
BRL Level:
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Sustainable Development Goal:
SDG03: Good health and well-being
Applications

Hydrogel formed with poly(ethylene)glycol (PEG) combined with heparin and a positively charged immune molecule, ands its use in T cell culture and immunotherapies.

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