Production of hyaluronic acid oligosaccharides using a novel fungal enzyme

Patent number:

EP25382020

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Enzymatic technology based on a novel fungal activity expressed in Pichia pastoris enabling controlled production of hyaluronic acid oligosaccharides (HAOS) in 2–3 hours under mild conditions. Produces defined mixtures of saturated and unsaturated fragments with tunable molecular profile; lab-validated.

Countries:

Spain

Regions:

Community of Madrid

Centers:

CSIC

Other entities:

CBM-(UAM/CSIC)

Sectors:

Chemicals

Health

Subsectors:

Materials

TRL Level:

TRL 4 – technology validated in lab

BRL Level:

BRL4: First version of business model, first projections of economic viability & market potential

PDF Link:

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Video Link:

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Sustainable Development Goal:

SDG03: Good health and well-being

Applications

Producción rápida y eficiente (2–3 h). Enzima heteróloga en Pichia pastoris: escalable y segura. Proceso libre de origen animal; ajustable a perfil molecular deseado. Aplicaciones en cosmética (ingredientes HAOS), medicina regenerativa y formulaciones farmacéuticas.

Comments

Tecnología alineada con demanda ética y regulatoria de procesos libres de origen animal; buena candidata para licenciamiento o codesarrollo con compañías de bioprocesos y cosmética.

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