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- Use of the tas1r3 protein as a marker for therapeutic, diagnostic, and/or prognostic purposes for tumors that express said protein
EP18382013; US20210275680A1
The invention presents the use of the TAS1R3 protein as a new marker and molecular target in epithelial tumors and other human pathologies. In particular, the use of the detection of the TAS1R3 protein as well as its expression products, as a marker for therapeutic, diagnostic or prognostic purposes, for tumors that normally express said protein is part of the present invention.
The present invention provides a new biomarker that is differentially expressed at the cell membrane of both primary tumor cells and disseminated cells. Additionally, the expression of this biomarker is related to tumorigenic capacity of tumor cells, increasing this expression especially in conditions of absence of nutrients, which would allow the use of this biomarker for the diagnosis/prognosis of cancer.