Compounds for the treatment of neurodegenerative and/or cardiovascular diseases

Patent number:

P202430463

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Countries:
Spain
Regions:
Community of Madrid
Centers:
CSIC
Other entities:
Sectors:
Health
Subsectors:
Pharmaceuticals
TRL Level:
TRL 3 – experimental proof of concept
BRL Level:
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Sustainable Development Goal:
Applications

Son neuroprotectores frente a la alfa-sinucleina en un modelo murino de enfermedad de Parkinson mediante administración intraperitoneal crónica. Se ha demostrado su eficacia frente a inflamación y daño vascular en un modelo murino de daño agudo pulmonar in vivo, inducido por LPS, y en modelos de hipertensión arterial y pulmonar. Administración por vía intra peritoneal u oral. Se han realizado estudios de farmacocinética in vivo mediante administración oral e intra peritoneal.

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