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Diagnostic procedure for the determination of the Nox2 protein
Patent number:
EP3495821A1
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A diagnostic method for the quantitative detection of the Nox2 protein in a biological sample, comprises the following operations i) normalize the protein content of the biological sample to a value of 1 μg of protein per 100 μl of the sample, ii) put in contacting the normalized biological sample with an anti-Nox2 monoclonal detection antibody, wherein the detection antibody is directly conjugated to a detection label, and iii) detecting the formation of the Nox2 protein-detection antibody complex
Countries:
Italy
Regions:
No items found.
Centers:
SAPIENZA UNIVERSITA DI ROMA
Other entities:
Sectors:
Health
Subsectors:
Biotechnology, Measurement, Analysis of biological materials
TRL Level:
TRL 7 – system prototype demonstration in operational environment
BRL Level:
BRL1: Hypothesizing on possible business concept
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Applications
This patent is applicable in the field of cardiovascular and inflammatory disease. In particular, analysing this biomarker (sNox2-dp) by ELISA kit is essential to stratify the cardiovascular and inflammatory risk.
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