EyeTBI: Portable Eye-Safe Spectroscopic Device for Rapid Traumatic Brain Injury Diagnosis

EyeTBI is a handheld, non-invasive medical device that uses Raman spectroscopy of the retina to detect molecular fingerprints associated with brain injury. Combined with our AI-driven SKiNET algorithm, the device provides immediate, objective assessment of TBI severity. Preclinical studies in murine and porcine models demonstrate 84% classification accuracy, validating the retina as a reliable surrogate for biochemical changes in the brain. The platform integrates fundus imaging and low-power, eye-safe lasers, enabling rapid, real-time detection of key biomarkers such as Cardiolipin, Cytochrome C, GFAP, and S100B. EyeTBI represents the first point-of-care, portable diagnostic system capable of detecting TBIs outside hospital settings.

EyeTBI is designed for pre-hospital and point-of-care use by first responders, paramedics, sports medics, and military personnel to rapidly triage patients with suspected brain injury. By providing real-time, objective results at the scene, it guides urgent transport decisions, reduces unnecessary CT scans, and accelerates clinical intervention. The device has broad applicability across emergency medicine, sports, defence, remote healthcare, and low-resource settings. Its AI-assisted analysis ensures rapid decision-making without the need for specialist expertise, improving patient outcomes, reducing healthcare costs and enabling scalable deployment worldwide.
Every year, millions suffer traumatic brain injuries (TBI), yet early diagnosis is slow, hospital-bound, and often missed. EyeTBI changes that. Our handheld, eye-safe device uses Raman spectroscopy to read molecular fingerprints in the retina - an optical window into the brain - combined with AI-driven analysis to deliver instant, objective TBI detection. Preclinical tests show 84-93% accuracy in identifying brain injury biomarkers.
EyeTBI empowers paramedics, sports medics, and military personnel to triage patients on-site, guiding urgent care, reducing unnecessary CT scans and improving outcomes. It’s rapid, non-invasive, low-cost, and scalable - poised to transform emergency and remote care globally.



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