Foldable paper-based devide for detection of infection in body fluids

A new and simple foldable paper-based fluidic device (InfectCheck), designed with only two foldable sections for an efficient separation and detection of the desired biomarker. Industrial Partners from biomedical sector to further develop the device and/or to establish commercial agreements are sought Chronic wounds represent a challenge to wound care professionals and consume a great deal of healthcare resources around the globe. The severity and cost of wound infections increase dramatically the longer they remain untreated. The resulting pain, impairment and social isolation lead to reduced quality of life and, in the worst case, hospitalization, and eventually sepsis and death. Standard procedures for wound infection detection are time consuming (microbiological tests) or show limited reliability due to the subjective judgement. Based on the medical practitioners interests, InfectCheck has been developed. of simple point of care testing (PoCT) devices based on the objective. InfectChek is a foldable paper-based fluidic device for detection of infection-related enzyme biomarkers in body fluids. InfectChek is designed to implement a highly specific immuno-capturing of an enzyme biomarker, followed by fast color development due to the enzyme activity. The colour in- tensity reveals the state of infection. InfectChek is validated for detection of infection in chronic wound exudates and sputum measuring the levels of myeloperoxidase (MPO) enzyme biomarker.