FUNCTIONALIZED ISONITRILES AND PRODUCTS, PREPARATION AND USES THEREOF

Patent number:

EP4178948A2

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The present invention relates to functionalized isonitrile compounds, formed by means of multicomponent environmentally friendly reactions, suitable for coupling to functional molecules such as biomolecules, APIs, chromophore and fluorophore molecules. The invention also relates to conjugates between said isonitrile compounds and functional molecules, which are useful in the synthesis of pharmaceutic drugs or tools, fluorescent molecules and labels, polymeric smart materials. The invention furthermore provides a kit for the in-vitro preparation of the functionalized isontrile compounds and conjugates. The invention also contemplates the medical use of said compounds and conjugates.

Countries:
Spain
Regions:
Galicia
Centers:
UNIVERSIDAD DE SANTIAGO DE COMPOSTELA
Other entities:
Sectors:
Health
Subsectors:
TRL Level:
TRL 5 – technology validated in relevant environment (industrially relevant environment in the case of key enabling technologies)
BRL Level:
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Sustainable Development Goal:
Applications

The inventors have used new methods for the synthesis of functionalized isonitriles. The isonitriles of the invention are particularly useful for the study and manipulation of biological systems and further development of new functional materials.

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