PHARMACEUTICAL COMPOSITION FOR USE IN THE PROPHYLACTIC AND/OR THERAPEUTIC TREATMENT OF L-DOPA-INDUCED DYSKINESIA

Patent number:

US11337985B2

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Pharmaceutical composition for use in the prophylactic and/or therapeutic treatment of dyskinesias induced by L-DOPA. The present invention relates to the pharmaceutical field, more particularly to the use of Rho kinase inhibitors for treating or preventing dyskinesias induced by L-DOPA.

Countries:

Spain

Regions:

Galicia

Centers:

UNIVERSIDAD DE SANTIAGO DE COMPOSTELA

Other entities:

Sectors:

Health

Subsectors:

TRL Level:

TRL 4 – technology validated in lab

BRL Level:

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Sustainable Development Goal:

Applications

The results that are presented in this document demonstrate that inhibition of the RhoA/Rho kinase (ROCK) pathway makes it possible to treat and/or prevent the dyskinesias that may be caused by chronic treatment with L-DOPA, administered to patients with Parkinson's disease.

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