MAGNETIC NANOPARTICLES FOR USE IN THE TREATMENT OF TUMORS

As demonstrated in the experimental part that follows, the nanoparticles of the invention are actually internalized by the cells of these tumors and, once inside the lysosomes, the decrease in pH promotes the release of the chemotherapeutic agent in the cytosol of the cell, from which it migrates in the nucleus where it damages the DNA. At the same time, the application of an external alternating magnetic field induces the heating of the nanocubes with consequent damage to the cellular structures due to heat. The two concomitant actions of heating and DNA damage by the drug induce then the cell's death.